Tesamorelin

Tesamorelin is a synthetic peptide analogue of human growth hormone-releasing hormone (GHRH 1-44). Researchers use it to study how GHRH receptors in the pituitary respond to a stabilized ligand. Project Amino supplies research-grade tesamorelin for laboratory use only.

For laboratory research use only. Not for human or veterinary use.

Tesamorelin at a Glance

• Type: synthetic 44-amino-acid GHRH analogue
• Key feature: trans-3-hexenoic acid group at the N-terminus, which improves stability against enzyme breakdown
• Target studied: pituitary GHRH receptor
• Form: lyophilized powder in a sealed vial
• Grade: 99%+ purity, COA per batch

What Is Tesamorelin?

• Tesamorelin has the same 44-amino-acid sequence as natural GHRH.
• One change sets it apart: a trans-3-hexenoic acid group added to the first amino acid.
• That change helps the peptide resist breakdown by the enzyme DPP-4, so it stays intact longer in study models.
• In plain terms: it is a sturdier copy of a natural signaling peptide, which makes it useful for receptor research.

Research Areas

• GHRH receptor binding: how a stabilized analogue binds and activates pituitary GHRH receptors
• GH–IGF-1 axis signaling: downstream signaling measured in controlled models
• Peptide stability: how N-terminal modification changes enzyme resistance and half-life in vitro
• Pituitary cell models: somatotroph cell response in laboratory studies

A pharmacology review is available here: Dhillon S (2011), PubMed.

Specifications

Quality and Testing

• Purity: minimum 99%, confirmed by HPLC
• Identity: confirmed by mass spectrometry
• Testing: independent third-party lab, every batch
• Documents: certificate of analysis (COA) per batch on the product certificates page
• Made in: USA

Lab Storage

• Keep sealed lyophilized powder cold, dry and away from light.
• Refrigerate reconstituted solution at 2–8 °C.
• Record batch number, concentration and date for traceability.

Related Research Materials

• Grow Blend research formulation
• Batch certificates of analysis

Frequently Asked Questions

What is tesamorelin?

Tesamorelin is a synthetic analogue of growth hormone-releasing hormone (GHRH 1-44) with an N-terminal trans-3-hexenoic acid group. It is used in laboratory research on GHRH receptor signaling.

How is tesamorelin different from natural GHRH?

It has the same sequence, plus a modification on the first amino acid that helps it resist enzyme breakdown, so it stays stable longer in study models.

What purity is Project Amino tesamorelin?

Minimum 99%, confirmed by HPLC, with identity confirmed by mass spectrometry and a third-party COA for every batch.

How should tesamorelin be stored in the lab?

Keep the sealed powder cold, dry and dark. Refrigerate reconstituted solution at 2–8 °C.

Is research-grade tesamorelin for human use?

No. It is sold for laboratory research only and is not for human or veterinary use.

Important Regulatory Notice

Tesamorelin sold by Project Amino is a research chemical for laboratory and research use only. It is not a drug, supplement or medical product, and it is not approved by the FDA. It is not intended for human or veterinary use, or for the diagnosis, treatment, cure or prevention of any disease. All statements summarize published research and are for educational purposes only. Purchasers must be 21 or older and are responsible for compliant handling.